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KSCC業績集 論文

1.
Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy
without radiotherapy for locally advanced rectal cancer (KSCC1301)
Keisuke Miwa, Eiji Oki, Masanobu Enomoto, Keisuke Ihara, Koji Ando, Fumihiko Fujita, Masahiro Tominaga, Shinichiro Mori, Goro Nakayama,
Mototsugu Shimokawa, Hiroshi Saeki, Hideo Baba, Masaki Mori, Yoshito Akagi
BMC Cancer. 2021 Jan 5;21(1):23. doi: 10.1186/s12885-020-07766-5.
PMID: 33402130 PMCID: PMC7786922 DOI: 10.1186/s12885-020-07766-5

https://pubmed.ncbi.nlm.nih.gov/33402130/

2.
Trifluridine/tipiracil plus bevacizumab as a first-line treatment for elderly patients with metastatic colorectal cancer (KSCC1602):
A multicenter phase II trial.
Oki E, Makiyama A, Miyamoto Y, Kotaka M, Kawanaka H, Miwa K, Kabashima A, Noguchi T, Yuge K, Kashiwada T, Ando K, Shimokawa M, Saeki H,
Akagi Y, Baba H, Maehara Y, Mori M.
Cancer Med. 2020 Nov 29. doi: 10.1002/cam4.3618. Online ahead of print.
PMID: 33249761

https://pubmed.ncbi.nlm.nih.gov/33249761/

3.
Safety and efficacy of S-1 plus oxaliplatin 130 mg/m(2) combination therapy in patients with previously untreated HER2-negative unresectable, advanced,
or recurrent gastric/gastroesophageal junction cancer: a phase II trial (KSCC1501A).
Kashiwada T, Shinozaki K, Ueno S, Kawanaka H, Uno F, Okita Y, Fukahori M, Matsushita H, Emi Y, Shimokawa M, Makiyama A, Saeki H, Oki E, Maehara Y,
Mori M, Baba E; Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2020 Oct 21. doi: 10.1007/s10147-020-01803-w. Online ahead of print.
PMID: 33085058

https://pubmed.ncbi.nlm.nih.gov/33085058/

4.
RAD51 Expression as a Biomarker to Predict Efficacy of Preoperative Therapy and Survival for Esophageal Squamous Cell Carcinoma:
A Large-cohort Observational Study (KSCC1307).
Saeki H, Jogo T, Kawazoe T, Kamori T, Nakaji Y, Zaitsu Y, Fujiwara M, Baba Y, Nakamura T, Iwata N, Egashira A, Nakanoko T, Morita M, Tanaka Y,
Kimura Y, Shibata T, Nakashima Y, Emi Y, Makiyama A, Oki E, Tokunaga S, Shimokawa M, Mori M; Kyushu Study Group of Clinical Cancer (KSCC).
Ann Surg. 2020 May 29. doi: 10.1097/SLA.0000000000003975. Online ahead of print.
PMID: 32482981

https://pubmed.ncbi.nlm.nih.gov/32482981/

5.
Multicenter Cohort Study to Assess the Association Between Changes on Imaging and Outcome After Regorafenib Treatment (KSCC1603)
Eiji Oki, Masahiro Kawahira, Tetsuya Kusumoto, Satoshi Yuki, Kazuteru Hatanaka, Yoshimitsu Kobayashi, Akihiro Nishie, Satoshi Kawanami, Akitaka Makiyama,
Hiroshi Saeki, Sanae Sakamoto, Yoshito Komatsu, Mototsugu Shimokawa, Masaki Mori, Taito Esaki
Oncology. 2020 Jul 8;1-8. doi: 10.1159/000507814. Online ahead of print.
PMID: 32640458 DOI: 10.1159/000507814

https://pubmed.ncbi.nlm.nih.gov/32640458/

6.
Efficacy and feasibility of S-1 plus oxaliplatin (C-SOX) for treating patients with stage III colon cancer (KSCC1303): final analysis of 3-year disease-free survival.
Ando K, Emi Y, Miyanari N, Tsuji A, Sakai K, Sawai T, Imamura H, Mori S, Tokunaga S, Oki E, Saeki H, Kakeji Y, Akagi Y, Baba H, Maehara Y, Mori M; Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2020 Mar 18. doi: 10.1007/s10147-020-01646-5. [Epub ahead of print]
PMID: 32189156

https://www.ncbi.nlm.nih.gov/pubmed/32189156

7.
Multicenter phase II study of SOX plus trastuzumab for patients with HER2+ metastatic or recurrent gastric cancer: KSCC/HGCSG/CCOG/PerSeUS 1501B.
Yuki S, Shinozaki K, Kashiwada T, Kusumoto T, Iwatsuki M, Satake H, Kobayashi K, Esaki T, Nakashima Y, Kawanaka H, Emi Y, Komatsu Y, Shimokawa M, Makiyama A, Saeki H, Oki E, Baba H, Mori M.
Cancer Chemother Pharmacol. 2020 Jan;85(1):217-223. doi: 10.1007/s00280-019-03991-3. Epub 2019 Nov 25.
PMID: 31768696

https://www.ncbi.nlm.nih.gov/pubmed/31768696

8.
Skeletal muscle loss during systemic chemotherapy for colorectal cancer indicates treatment response: a pooled analysis of a multicenter clinical trial (KSCC 1605-A)
Shun Sasaki, Eiji Oki, Hiroshi Saeki, Takayuki Shimose, Sanae Sakamoto, Qingjiang Hu, Kensuke Kudo, Yasuo Tsuda, Yuichiro Nakashima, Koji Ando, Yoshito Akagi, Yoshihiro Kakeji, Hideo Baba,
Yoshihiko Maehara
Int J Clin Oncol. 2019 Oct;24(10):1204-1213. doi: 10.1007/s10147-019-01460-8. Epub 2019 May 6.
PMID: 31062115 DOI: 10.1007/s10147-019-01460-8

https://www.ncbi.nlm.nih.gov/pubmed/31062115

9.
Comparison of computed tomography imaging analyses for evaluation after chemotherapy in patients with colorectal cancer: a retrospective pooled analysis of six phase II clinical trials.
Hirose K, Oki E, Shimose T, Sakamoto S, Sasaki S, Jogo T, Hu Q, Tsuda Y, Ando K, Nakashima Y, Saeki H, Mori M.
Int J Clin Oncol. 2019 Jul 22. doi: 10.1007/s10147-019-01509-8. [Epub ahead of print]
PMID: 31332611 DOI: 10.1007/s10147-019-01509-8

https://www.ncbi.nlm.nih.gov/pubmed/31332611

10.
Pancreatic cancer arising from the remnant pancreas after pancreatectomy: a multicenter retrospective study by the Kyushu Study Group of Clinical Cancer.
Hashimoto D, Arima K, Nakagawa S, Negoro Y, Hirata T, Hirota M, Inomata M, Fukuzawa K, Ohga T, Saeki H, Oki E, Yamashita YI, Chikamoto A, Baba H, Maehara Y.
J Gastroenterol. 2018 Dec 4. doi: 10.1007/s00535-018-01535-9. [Epub ahead of print]
PMID: 30515563

https://www.ncbi.nlm.nih.gov/pubmed/30515563

11.
Re-evaluation of HER2 status in patients with HER2-positive advanced or recurrent gastric cancer refractory to trastuzumab (KSCC1604).
Saeki H, Oki E, Kashiwada T, Arigami T, Makiyama A, Iwatsuki M, Narita Y, Satake H, Matsuda Y, Sonoda H, Shimokawa M, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Eur J Cancer. 2018 Dec;105:41-49. doi: 10.1016/j.ejca.2018.09.024. Epub 2018 Nov 2.
PMID: 30391779

https://www.ncbi.nlm.nih.gov/pubmed/30391779

12.
Prophylactic Effect of Dexamethasone on Regorafenib-Related Fatigue and/or Malaise: A Randomized, Placebo-Controlled, Double-Blind Clinical Study in Patients with Unresectable Metastatic Colorectal Cancer (KSCC1402/HGCSG1402).
Tanioka H, Miyamoto Y, Tsuji A, Asayama M, Shiraishi T, Yuki S, Kotaka M, Makiyama A, Shimokawa M, Shimose T, Masuda S, Yamaguchi T, Komatsu Y, Saeki H, Emi Y, Baba H, Oki E, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Oncology. 2018 Mar 7. doi: 10.1159/000486624. [Epub ahead of print]
PMID: 29514163

https://www.ncbi.nlm.nih.gov/pubmed/29514163

13.
Study protocol of a phase II clinical trial (KSCC1501A) examining oxaliplatin + S-1 for treatment of HER2-negative advanced/recurrent gastric cancer previously untreated with chemotherapy.
Saeki H, Emi Y, Oki E, Tokunaga S, Kakeji Y, Akagi Y, Baba H, Baba E, Maehara Y; Kyushu Study group of Clinical Cancer (KSCC).
BMC Cancer. 2018 Jan 8;18(1):57. doi: 10.1186/s12885-017-3937-6.
PMID: 29310611

https://www.ncbi.nlm.nih.gov/pubmed/29310611

14.
Low Visceral Fat Content Is a Negative Predictive Marker for Bevacizumab in Metastatic Colorectal Cancer.
Miyamoto Y, Oki E, Emi Y, Tokunaga S, Shimokawa M, Ogata Y, Akagi Y, Sakamoto Y, Tanaka T, Saeki H, Maehara Y, Baba H
Anticancer Res. 2018 Jan;38(1):491-499
PMID: 29277814

https://www.ncbi.nlm.nih.gov/pubmed/29277814

15.
A prospective study of XELIRI plus bevacizumab as a first‑line therapy in Japanese patients with unresectable or recurrentcolorectal cancer (KSCC1101)
Ando K, Emi Y, Suenaga T, Hamanoue M, Maekawa S, Sakamoto Y, Kai S, Satake H, Shimose T, Shimokawa M, Saeki H, Oki E, Sakai K, Akagi Y, Baba H, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2017 May 19. doi: 10.1007/s10147-017-1140-z. [Epub ahead of print]
PMID:28526907

https://www.ncbi.nlm.nih.gov/pubmed/28526907

16.
Final report of KSCC0803: feasibility study of capecitabine as adjuvant chemotherapy for stage III colon cancer in Japan.
Minami K, Morita M, Emi Y, Okamoto M, Tanaka E, Nagata S, Touyama T, Ohgaki K, Tanaka T, Okumura H, Suenaga T, Tokunaga S, Oki E, Kakeji Y, Akagi Y, Baba H, Natsugoe S, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2017 Jan 18. doi: 10.1007/s10147-017-1088-z. [Epub ahead of print]
PMID: 28101757

https://www.ncbi.nlm.nih.gov/pubmed/28101757

17.
Phase II trial of capecitabine plus modified cisplatin (mXP) as first-line therapy in Japanese patients with metastatic gastric cancer (KSCC1104).
Satake H, Iwatsuki M, Uenosono Y, Shiraishi T, Tanioka H, Saeki H, Sugimachi K, Kitagawa D, Shimokawa M, Oki E, Emi Y, Kakeji Y, Tsuji A, Akagi Y, Natsugoe S, Baba H, Maehara Y; Kyushu Study Group of Clinical Cancer.
Cancer Chemother Pharmacol. 2017 Jan;79(1):147-153. doi: 10.1007/s00280-016-3204-6.
PMID: 27942930

https://www.ncbi.nlm.nih.gov/pubmed/27942930

18.
Expression of the anaphylatoxin C5a receptor in gastric cancer: implications for vascular invasion and patient outcomes.
Nitta H, Shimose T, Emi Y, Imamura T, Ohnishi K, Kusumoto T, Yamamoto M, Fukuzawa K, Takahashi I, Higashi H, Tsuji A, Akagi Y, Oki E, Maehara Y, Baba H; Kyushu Study Group of Clinical Cancer (KSCC) ancillary study.
Med Oncol. 2016 Nov;33(11):118. doi: 10.1007/s12032-016-0834-9. Epub 2016 Sep 29.
PMID: 27688239

https://www.ncbi.nlm.nih.gov/pubmed/27688239

19.
Multicenter phase II study of combination therapy with cetuximab and S-1 in patients with KRAS exon 2 wild-type unresectable colorectal cancer previously treated with irinotecan, oxaliplatin, and fluoropyrimidines (KSCC 0901 study).
Takahashi T, Emi Y, Oki E, Kobayashi K, Tsuji A, Shimokawa M, Tanaka T, Akagi Y, Ogata Y, Baba H, Yoshida K, Natsugoe S, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Cancer Chemother Pharmacol. 2016 Jul 28. [Epub ahead of print]
PMID:27468920

http://www.ncbi.nlm.nih.gov/pubmed/27468920

20.
Surgical treatment of liver metastasis of gastric cancer: a retrospective multicenter cohort study (KSCC1302).
Oki E, Tokunaga S, Emi Y, Kusumoto T, Yamamoto M, Fukuzawa K, Takahashi I, Ishigami S, Tsuji A, Higashi H, Nakamura T, Saeki H, Shirabe K, Kakeji Y, Sakai K, Baba H, Nishimaki T, Natsugoe S, Maehara Y; Kyushu Study Group of Clinical Cancer.
Gastric Cancer. 2016 Jul;19(3):968-76. doi: 10.1007/s10120-015-0530-z. Epub 2015 Aug 11.
PMID: 26260876

http://www.ncbi.nlm.nih.gov/pubmed/26260876

21.
A prospective study of XELOX plus bevacizumab as first-line therapy in Japanese patients with metastatic colorectal cancer (KSCC 0902).
Ogata Y, Shimokawa M, Tanaka T, Emi Y, Oki E, Saeki H, Sadanaga N, Kusumoto T, Touyama T, Kimura M, Baba H, Akagi Y, Shirouzu K, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2016 Apr;21(2):335-43. doi: 10.1007/s10147-015-0895-3. Epub 2015 Sep 4.
PMID: 26338269

http://www.ncbi.nlm.nih.gov/pubmed/26338269

22.
Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study.
Takatsuki M, Tokunaga S, Uchida S, Sakoda M, Shirabe K, Beppu T, Emi Y, Oki E, Ueno S, Eguchi S, Akagi Y, Ogata Y, Baba H, Natsugoe S, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Eur J Surg Oncol. 2016 Feb;42(2):184-9. doi: 10.1016/j.ejso.2015.11.007. Epub 2015 Nov 22.
PMID: 26683263

http://www.ncbi.nlm.nih.gov/pubmed/26683263

23.
Phase II trial of an alternating regimen consisting of first-line mFOLFOX6 plus bevacizumab and FOLFIRI plus bevacizumab for patients with metastatic colorectal cancer: FIREFOX plus bevacizumab trial (KSCC0801).
Miwa K, Oki E, Emi Y, Saeki H, Kusumoto T, Akagi Y, Ogata Y, Samura H, Tokunaga S, Ishikawa H, Tanaka T, Sueyoshi S, Higashi H, Matsuda H, Touyama T, Maehara Y; Kyushu Study Group of Clinical Cancer.
Int J Clin Oncol. 2016 Feb;21(1):110-7. doi: 10.1007/s10147-015-0850-3. Epub 2015 Jun 3.
PMID:26037783

http://www.ncbi.nlm.nih.gov/pubmed/26037783

24.
S-1 and irinotecan plus bevacizumab as second-line chemotherapy for patients with oxaliplatin-refractory metastatic colorectal cancer: a multicenter phase II study in Japan (KSCC1102).
Miyamoto Y, Tsuji A, Tanioka H, Maekawa S, Kawanaka H, Kitazono M, Oki E, Emi Y, Murakami H, Ogata Y, Saeki H, Shimokawa M, Natsugoe S, Akagi Y, Baba H, Maehara Y.
Int J Clin Oncol. 2016 Jan 8. [Epub ahead of print]
PMID:26746689

http://www.ncbi.nlm.nih.gov/pubmed/26746689

25.
Phase II Trial of S-1 and Oxaliplatin Plus Cetuximab for Colorectal Cancer Patients with Initially Unresectable or Not Optimally Resectable Liver Metastases (KSCC1002).
Oki E, Emi Y, Miyamoto Y, Kabashima A, Higashi H, Ogata Y, Ikebe M, Saeki H, Tokunaga S, Shirabe K, Beppu T, Uchida S, Takatsuki M, Sakoda M, Eguchi S, Akagi Y, Kakeji Y, Baba H, Natsugoe S, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1067-74. doi: 10.1245/s10434-015-4771-1. Epub 2015 Sep 3.
PMID:26334293

http://www.ncbi.nlm.nih.gov/pubmed/26334293

26.
Liver resectability of advanced liver-limited colorectal liver metastases following mFOLFOX6 with bevacizumab (KSCC0802 Study).
Beppu T, Emi Y, Tokunaga S, Oki E, Shirabe K, Ueno S, Kuramoto M, Kabashima A,
Takahashi I, Samura H, Eguchi S, Akagi Y, Natsugoe S, Ogata Y, Kakeji Y, Baba H, Maehara Y; Kyushu Study group of Clinical Cancer (KSCC).
Anticancer Res. 2014 Nov;34(11):6655-62.
PMID:25368271[PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/25368271

27.
Impact of second-line and later cetuximab-containing therapy and KRAS genotypes in patients with metastatic colorectal cancer: a multicenter study in Japan.
Saeki H, Emi Y, Kumashiro R, Otsu H, Kawano H, Ando K, Ida S, Kimura Y, Tokunaga E, Oki E, Morita M, Shimokawa M, Maehara Y.
Surg Today. 2014 Aug;44(8):1457-64. doi: 10.1007/s00595-013-0716-0. Epub 2013 Sep 8.
PMID:24013837[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24013837

28.
Splenic volume may be a useful indicator of the protective effect of bevacizumab against oxaliplatin-induced hepatic sinusoidal obstruction syndrome.
Imai K, Emi Y, Iyama KI, Beppu T, Ogata Y, Kakeji Y, Samura H, Oki E, Akagi Y, Maehara Y, Baba H; Kyusyu Study Group of Clinical Cancer (KSCC) ancillary study.
Eur J Surg Oncol. 2014 May;40(5):559-66. doi: 10.1016/j.ejso.2013.12.009. Epub 2013 Dec 20.
PMID:24388740[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24388740

29.
Phase II trial of alternating mFOLFOX6 and FOLFIRI regimens in the first-line treatment for unresectable or metastatic colorectal cancer (KSCC0701).
Oki E, Emi Y, Akagi Y, Tokunaga S, Sadanaga N, Tanaka T, Ogata Y, Saeki H, Kakeji Y, Baba H, Nishimaki T, Natsugoe S, Shirouzu K, Maehara Y; Kyushu Study Group of Clinical Cancer.
Oncology. 2013;84(4):233-9. doi: 10.1159/000346690. Epub 2013 Jan 31.
PMID:23392220[PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/23392220

30.
Initial report of KSCC0803: feasibility study of capecitabine as adjuvant chemotherapy for stage III colon cancer in Japanese patients.
Emi Y, Kakeji Y, Oki E, Saeki H, Ando K, Kitazono M, Sakaguchi Y, Morita M, Samura H, Ogata Y, Akagi Y, Natsugoe S, Shirouzu K, Tokunaga S, Sirzen F, Maehara Y;
Kyushu Study Group of Clinical Cancer (KSCC).
Int J Clin Oncol. 2013 Apr;18(2):254-9. doi: 10.1007/s10147-011-0371-7. Epub 2012 Jan 13.
PMID:22240888[PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/22240888

31.
A multicenter phase II clinical study of oxaliplatin, folinic acid, and 5-fluorouracil combination chemotherapy as second-line treatment for advanced colorectal cancer: a Japanese experience.
Ogata Y, Tokunaga S, Emi Y, Oki E, Saeki H, Shirabe K, Hasegawa H, Sadanaga N, Samura H, Fujita F, Tanaka T, Kitazono M, Yamamoto M, Morikita T, Inomata M, Kakeji Y, Shirouzu K, Maehara Y; Kyushu Study Group of Clinical Cancer.
Surg Today. 2011 Jan;41(1):84-90. doi: 10.1007/s00595-010-4418-6. Epub 2010 Dec 30.
PMID: 21191696

https://www.ncbi.nlm.nih.gov/pubmed/21191696

32.
A multicenter phase II clinical study of oxaliplatin, folinic acid, and 5-fluorouracil combination chemotherapy as first-line treatment for advanced colorectal cancer: a Japanese experience.
Baba H, Hayashi N, Emi Y, Kakeji Y, Egashira A, Oki E, Shirabe K, Toyama T, Ohga T, Yamamoto M, Hasegawa H, Kohakura F, Higashi H, Niwa K, Fujita F, Ogata Y, Kohnoe S, Inomata M, Samura H, Tokunaga S, Maehara Y; Kyushu Study Group of Clinical Cancer (KSCC).
Surg Today. 2011 Dec;41(12):1610-6. doi: 10.1007/s00595-011-4589-9. Epub 2011 Oct 4.
PMID:21969193[PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/21969193